This product has been classified in accordance with the hazard criteria of the controlled. Acetylsalicylic acid side effects, uses, dosage, overdose. Although not all of these side effects may occur, if they do occur they may need medical attention. Aspirin is the common name for the compound acetylsalicylic acid, widely used as a fever reducer and as a pain killer. Relevant identified uses of the substance or mixture and uses advised against. Ac158180000, ac158180500, ac158185000, ac385760000 synonyms. Determination of acetylsalicylic acid in aspirin using. Causes irritation of the mucous membrane and upper respiratory tract. See salicylate for adverse reactions and poisoning. Specific inflammatory conditions which aspirin is used to treat include kawasaki disease, pericarditis, and rheumatic fever.
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Files are available under licenses specified on their description page. Salicylic acid was measured at 24 hours following a single dose of extendedrelease acetylsalicylic acid f4405. Safety data sheet according to 29cfr19101200 and ghs rev.
Aspirin is an orally administered nonsteroidal antiinflammatory agent. Acetylsalicylic acid is hydrolyzed in the plasma to salicylic acid. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters 150 feet for liquids and at least 25 meters 75 feet for solids. Salicylic acid, whose name comes from salix, the willow family of plants, was derived from willow bark extracts. I know that acetylsalicylic acid isnt very soluble in water. It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. Indication of any immediate medical attention and special treatment needed see section 4. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910. Safety data sheet acetylsalicylic acid acylbdglucuronide according to regulation ec no 19072006, annex ii, as amended. Get a printable copy pdf file of the complete article 766k, or click on a page image below to browse page by page. The information in cameo chemicals comes from a variety of data sources. Ac158180000, ac158180025, ac158185000, ac385760000 synonyms.
Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Safety data sheet acetylsalicylic acidacylbdglucuronide according to regulation ec no 19072006, annex ii, as amended. Product identifier product name acetylsalicylic acid acylbdglucuronide. The phenomenon of fluorescence in most cases represents the. How many 80mg aspirin tablets would a 160 pound person have to consume to ingest the estimated ld50 for acetylsalicylic acid. Acetylsalicylic acid definition of acetylsalicylic acid by.
Sigmaaldrich offers a number of acetylsalicylic acid products. Severe salicylate intoxication may cause central nervous system disturbances such as convulsions and coma, skin eruptions, and alteration in the acid base balance. However, we make no warranty of merchantability or any other. 1 toxicity toxicity to fish lc50 leuciscus idus golden orfe 1,000 mgl 48 ho acetylsalicylic acid. Acetylsalicylic acid aspirin, a prodrug to salicylic acid, is made by an entirely different process. Plasma concentrations of aspirin following after administration of the extendedrelease form are mostly undetectable 48 hours after ingestion of a single dose. Safety data sheet malic acid revision 7 01122014 en irritating to eyes and skin. Acetic acid, glacial alcohol of vinegar carboxylic acid c2 ethanoic acid ethylic acid methanecarboxylic acid pyroligneous acid vinegar acid. Aspirin, also known as acetylsalicylic acid asa, is a medication used to reduce pain, fever, or inflammation. All structured data from the file and property namespaces is available under the creative commons cc0 license. Show this safety data sheet to the doctor in attendance. Buy acetylsalicylic anhydride cas 1466826, impurity d of acetylsalicylic acid, from santa cruz.
Oacetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. Precautionary statements p261 avoid breathing dust. Commission regulation eu no 2015830 of 28 may 2015. Salicylic acid and its esters are used as food preservatives, in skincare products and other cosmetics, and in topical medicines.
Along with its needed effects, aspirin the active ingredient contained in acetylsalicylic acid may cause some unwanted effects. Safety data sheet chandlergilbert community college. E29 preparation of aspirin acetylsalicylic acid and thinlayer chromatography of analgesic drugs the task to prepare a pharmaceutical compound and test its purity. Excerpt from erg guide 154 substances toxic andor corrosive noncombustible. Determination of acetylsalicylic acid in aspirin using total fluorescence spectroscopy application note author melissa quinn agilent technologies, inc. Salicylic acid 2hydroxybenzoic acid is a white solid first isolated from the bark of willow trees salix spp. Acetylsalicylic acid get uptodate information on acetylsalicylic acid side effects, uses, dosage, overdose, pregnancy, alcohol and more. Check with your doctor immediately if any of the following side effects occur while taking aspirin. Acetic acid, glacial alcohol of vinegar carboxylic acid c2 ethanoic acid ethylic acid methanecarboxylic acid pyroligneous acid vinegar acid 1. Acetylsalicylic acid api manufacturers suppliers drug. Pharmacokinetics and pharmacodynamics of acetylsalicylic. Fisher scientific one reagent lane fair lawn, nj 07410. E29 preparation of aspirin acetylsalicylic acid and thin. Sds of acetylsalicylic acid, safety data sheets, cas 50782.
You also can through below form to request documents for moa,ros,1hnmr. Introduction fluorescence is the emission of light by a molecule in an excited electronic state. O acetylsalicylic acid 2acetoxybenzoic acid aspirin formula. Synthesis of acetylsalicylic acid dan jones, josh schmidt abstract acetylsalicylic acid, commonly known as aspirin, is considered to be the most successful pharmaceutical product in the world. In some countries, this medicine may only be approved for veterinary use.
This product contains acetylsalicylic acid, a chemical known to the state of california to cause female reproductive toxicity. Safety data sheet acetylsalicylic acidacylbdglucuronide. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Our msds database is an easy to use, do it yourself tool, and best of all. Aspirin should not be given to children who have viral infections, because this has been associated with the subsequent development of reyes syndrome. In a business making drugs based on, for example, acetylsalicylic acid, a product that has been on the market for well over 100 years, the chances are there is often no new knowledge to be gained from psurs periodic safety update reports and single case handling, yet the dogged reporting and analysis still has to take place in order to. The skills by the end of the experiment you should be able to. Media in category acetylsalicylic acid the following 59 files are in this category, out of 59 total. Links to pubmed are also available for selected references. For this reason, it is industrially synthesized on a massive scale, producing up.
Acetylsalicylic acid not listed as a carcinogen by acgih, iarc, ntp, or ca prop 65. Product identifier product name acetylsalicylic acidacylbdglucuronide. Ive tried researching on the net and so far i havent really got it, but i think im onto something. Oacetylsalicylic acid 2acetoxybenzoic acid aspirin formula. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Identification of the substancemixture and of the companyundertaking 1. First aid measures always seek professional medical attention after first aid measures are provided.
Water is a polar molecule, and i think acetylsalicylic acid isnt. Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. In folk medicine, willow bark teas were used as headache remedies and other tonics. The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents.
Material safety data sheet acetylsalicylic acid product observe all federal, state, and local environmental regulations. Jul 27, 2017 acetylsalicylic acid get uptodate information on acetylsalicylic acid side effects, uses, dosage, overdose, pregnancy, alcohol and more. Other information prepared by regulatory affairs thermo fisher scientific email. O acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. The msds sheet for acetylsalicylic acid estimates its oral, single dose ld50 as 357 mg per kg in humans. Aspirin given shortly after a heart attack decreases the risk of death. It also occurs as the free acid or its esters in many plant species. Curiously, salicylic acid is also a metabolite of aspirin. Full text full text is available as a scanned copy of the original print version. In case of skin contact wash off with soap and plenty of water. Contact a licensed professional waste disposal service to dispose of this material.
Extinguishing media appropriate firefighting equipment. This agent exhibits analgesic, antipyretic, and anticoagulant properties. In the us, acetylsalicylic acid is a member of the following drug classes. Acetylsalicylic acid solubilty organic chemistry science. Pharmacokinetics and pharmacodynamics of acetylsalicylic acid after intravenous and oral administration to healthy volunteers j nagelschmitz,1 m blunck,1 j kraetzschmar,1 m ludwig,1 g wensing,1 t hohlfeld2 1bayer healthcare ag, clinical pharmacology, wuppertal, germany. Determination of acetylsalicylic acid in aspirin using total. If inhaled if breathed in, move person into fresh air. Safety data sheet northwest missouri state university. If ingestion has occurred less than 2 hours earlier, carry out careful gastric lavage. Acetylsalicylic acid definition of acetylsalicylic acid. Material safety data sheet page 1 of 2 acetylsalicylic acid. This product contains acetylsalicylic acid, a chemical known. A meta description is an html tag in the html code of your website, which allows you to customize a section of text that describes the page itself.
Physical and chemical properties molecular formula c9h8o4. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. Search results for acetylsalicylic acid at sigmaaldrich. Aspirin material safety data sheet cas no 50782 sdsmsds. This product contains materials that may cause severe pneumonitis if aspirated.
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